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Synvisc-One Information

Synvisc-One® (hylan G-F 20) and SYNVISC® (hylan G-F 20) are indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

Synvisc-One Videos

Injection Technique Animation

Inferolateral Injection Technique
Patient Injection
Timothy E. Kremchek, M.D.
Beacon Orthopaedics & Sports Medicine
Medical Director & Chief Orthopaedic Surgeon for the Cincinnati Reds

Superolateral Injection Technique
Patient Injection
Jason Rand, P.A.
Boston Sports & Shoulder Center

Injection Technique Discussion
Amy P. Powell, M.D.
Sports Medicine

Patient Expectations
Ralph A. Gambardella, M.D.
Kerlan-Jobe Orthopaedic Clinic



Patient Information

Important Safety Information
Before trying Synvisc-One or SYNVISC, tell your doctor if you are allergic to products from birds — such as feathers, eggs or poultry — or if your leg is swollen or infected. Synvisc-One and SYNVISC are only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One and SYNVISC have not been tested to show pain relief in joints other than the knee. Talk to your doctor before resuming strenuous weight-bearing activities after treatment. Synvisc-One and SYNVISC have not been tested in children, pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child. The side effects most commonly seen when Synvisc-One or SYNVISC is injected into the knee were pain, swelling and/or fluid buildup in or around the knee. Cases where the swelling is extensive or painful should be discussed with your doctor. Allergic reactions such as rash and hives have been reported rarely.